Vladimir Kagan was born on August 29, 1927, in Worms, Germany, The son of a Russian Jewish cabinetmaker, Vladimir Kagan's childhood was cut short by the rise of the Nazis. He emigrated to the United States in 1938. His early focus was painting and sculpture but in the following years he became eagerly attracted to architecture and design. Graduated from the School of Industrial Art in 1946, where he was an architecture major and then went on to study architecture at Columbia University.
In 1947 he joined his father Illi Kagan, a master cabinetmaker to work in his woodworking shop and learn furniture making from the ground up. In an interview he recalls his "father saying 'Measure three times and cut once'; I would be of the school of cut three times and never measure"
He opened his first personal shop in New York in 1949. In 1950 the Kagan-Dreyfus partnership began with a showroom/store on 125 East 57th Street in New York City. His early work included furniture for the Delegate's Cocktail Lounge at the United Nations and furniture for the "Monsanto House of the Future" at Disneyland.